在新时代育人方式变革与新课程改革深化的背景下，跨学科主题学习已成为培养学生核心素养、提升学生适应复杂现实世界挑战能力的关键路径。本文立足综合思维培养目标，聚焦地理与化学两大学科，选取兼具典型地貌形态与深刻化学过程的“喀斯特地貌”为载体，构建一套系统的跨学科教学设计方案，将不可见的微观化学过程转化为可感知的学习经验，帮助学生建立地貌形成的认知链条，构建“现象描述—微观机制—宏观演化—人地关系”的四阶融合框架，开发与综合思维三维度相匹配的教学评价量表，为自然地理跨学科教学提供了可操作的范式参考。

Against the backdrop of the transformation of educational approaches in the new era and the deepening of the new curriculum reform, interdisciplinary thematic learning has become an important approach to cultivating students’ core competencies and enhancing their ability to adapt the complex real-world challenges. Focusing on the goal of developing integrated thinking, this paper takes karst landforms as the teaching context to construct a systematic interdisciplinary instructional design integrating geography and chemistry. By transforming invisible microscopic chemical processes into perceptible learning experiences, it helps students establish a cognitive chain of landform formation. A four-stage interdisciplinary framework of“phenomenon description–microscopic mechanism–macroscopic evolution–human– environment relationship”is developed, together with a teaching evaluation rubric aligned with the three dimensions of integrated thinking, providing a practical reference for interdisciplinary teaching in physical geography.